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Reconsidering Medication Discontinuation After a First Episode of Psychosis


Dr. Robert Zipursky presents Grand Rounds at CAMH in April 2018

Learning objectives: Outline the different study methodologies used to determine recurrence rates following a first episode of psychosis, as well as their limitations; Describe the risk of recurrence with and without maintenance medications for individuals who have remitted from a first episode of psychosis; Describe the risk of developing schizophrenia and bipolar disorder when a person has a first episode of cannabis-induced psychosis. 

Dr. Zipursky joined the University of Toronto Department of Psychiatry in 1991 and established the First Episode Psychosis Program at the Clarke Institute of Psychiatry/CAMH, where he directed from 1992 to 2006. He served as the Director of the Schizophrenia Division from 1995-2006 and was the Tapscott Chair in Schizophrenia Studies at U of T. In 2007, Dr. Zipursky was appointed Chair of the department of Psychiatry and Behavioural Neurosciences at McMaster University. He returned to CAMH and the Department of Psychiatry at U of T in January 2018. 
Dr. Zipursky's research has involved the study of structural brain abnormalities in schizophrenia and other psychiatric disorders using MRI, optimal dosing of antipsychotic medication using PET, and outcomes from first epdisode psychosis and their determinants.